Hematologic, hepatic, and renal function changes in hospitalized patients with Middle East respiratory syndrome coronavirus.
Identifieur interne : 001A29 ( Ncbi/Merge ); précédent : 001A28; suivant : 001A30Hematologic, hepatic, and renal function changes in hospitalized patients with Middle East respiratory syndrome coronavirus.
Auteurs : J A Al-Tawfiq [Arabie saoudite] ; K. Hinedi [Arabie saoudite] ; S. Abbasi [Arabie saoudite] ; M. Babiker [Arabie saoudite] ; A. Sunji [Arabie saoudite] ; M. Eltigani [Arabie saoudite]Source :
- International journal of laboratory hematology [ 1751-553X ] ; 2017.
Descripteurs français
- KwdFr :
- Coronavirus du syndrome respiratoire du Moyen-Orient, Femelle, Foie (anatomopathologie), Foie (métabolisme), Hospitalisation, Humains, Hyperleucocytose (sang), Hyperleucocytose (virologie), Infections à coronavirus (anatomopathologie), Infections à coronavirus (sang), Mâle, Numération des leucocytes, Rein (anatomopathologie), Rein (métabolisme), Tests de la fonction rénale, Thrombopénie (sang), Thrombopénie (virologie), Études rétrospectives.
- MESH :
- anatomopathologie : Foie, Infections à coronavirus, Rein.
- métabolisme : Foie, Rein.
- sang : Hyperleucocytose, Infections à coronavirus, Thrombopénie.
- virologie : Hyperleucocytose, Thrombopénie.
- Coronavirus du syndrome respiratoire du Moyen-Orient, Femelle, Hospitalisation, Humains, Mâle, Numération des leucocytes, Tests de la fonction rénale, Études rétrospectives.
English descriptors
- KwdEn :
- Coronavirus Infections (blood), Coronavirus Infections (pathology), Female, Hospitalization, Humans, Kidney (metabolism), Kidney (pathology), Kidney Function Tests, Leukocyte Count, Leukocytosis (blood), Leukocytosis (virology), Liver (metabolism), Liver (pathology), Male, Middle East Respiratory Syndrome Coronavirus, Retrospective Studies, Thrombocytopenia (blood), Thrombocytopenia (virology).
- MESH :
- blood : Coronavirus Infections, Leukocytosis, Thrombocytopenia.
- metabolism : Kidney, Liver.
- pathology : Coronavirus Infections, Kidney, Liver.
- virology : Leukocytosis, Thrombocytopenia.
- Female, Hospitalization, Humans, Kidney Function Tests, Leukocyte Count, Male, Middle East Respiratory Syndrome Coronavirus, Retrospective Studies.
Abstract
There are no longitudinal data on the changes in hematologic, hepatic, and renal function findings in patients with Middle East respiratory syndrome coronavirus (MERS-CoV) infection.
DOI: 10.1111/ijlh.12620
PubMed: 28444873
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Hinedi</name><affiliation wicri:level="1"><nlm:affiliation>Internal Medicine, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.</nlm:affiliation><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Internal Medicine, Johns Hopkins Aramco Healthcare, Dhahran</wicri:regionArea><wicri:noRegion>Dhahran</wicri:noRegion></affiliation></author><author><name sortKey="Abbasi, S" sort="Abbasi, S" uniqKey="Abbasi S" first="S" last="Abbasi">S. Abbasi</name><affiliation wicri:level="1"><nlm:affiliation>Internal Medicine, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.</nlm:affiliation><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Internal Medicine, Johns Hopkins Aramco Healthcare, Dhahran</wicri:regionArea><wicri:noRegion>Dhahran</wicri:noRegion></affiliation></author><author><name sortKey="Babiker, M" sort="Babiker, M" uniqKey="Babiker M" first="M" last="Babiker">M. Babiker</name><affiliation wicri:level="1"><nlm:affiliation>Internal Medicine, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.</nlm:affiliation><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Internal Medicine, Johns Hopkins Aramco Healthcare, Dhahran</wicri:regionArea><wicri:noRegion>Dhahran</wicri:noRegion></affiliation></author><author><name sortKey="Sunji, A" sort="Sunji, A" uniqKey="Sunji A" first="A" last="Sunji">A. Sunji</name><affiliation wicri:level="1"><nlm:affiliation>Internal Medicine, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.</nlm:affiliation><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Internal Medicine, Johns Hopkins Aramco Healthcare, Dhahran</wicri:regionArea><wicri:noRegion>Dhahran</wicri:noRegion></affiliation></author><author><name sortKey="Eltigani, M" sort="Eltigani, M" uniqKey="Eltigani M" first="M" last="Eltigani">M. Eltigani</name><affiliation wicri:level="1"><nlm:affiliation>Internal Medicine, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.</nlm:affiliation><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Internal Medicine, Johns Hopkins Aramco Healthcare, Dhahran</wicri:regionArea><wicri:noRegion>Dhahran</wicri:noRegion></affiliation></author></analytic><series><title level="j">International journal of laboratory hematology</title><idno type="eISSN">1751-553X</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Coronavirus Infections (blood)</term><term>Coronavirus Infections (pathology)</term><term>Female</term><term>Hospitalization</term><term>Humans</term><term>Kidney (metabolism)</term><term>Kidney (pathology)</term><term>Kidney Function Tests</term><term>Leukocyte Count</term><term>Leukocytosis (blood)</term><term>Leukocytosis (virology)</term><term>Liver (metabolism)</term><term>Liver (pathology)</term><term>Male</term><term>Middle East Respiratory Syndrome Coronavirus</term><term>Retrospective Studies</term><term>Thrombocytopenia (blood)</term><term>Thrombocytopenia (virology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Coronavirus du syndrome respiratoire du Moyen-Orient</term><term>Femelle</term><term>Foie (anatomopathologie)</term><term>Foie (métabolisme)</term><term>Hospitalisation</term><term>Humains</term><term>Hyperleucocytose (sang)</term><term>Hyperleucocytose (virologie)</term><term>Infections à coronavirus (anatomopathologie)</term><term>Infections à coronavirus (sang)</term><term>Mâle</term><term>Numération des leucocytes</term><term>Rein (anatomopathologie)</term><term>Rein (métabolisme)</term><term>Tests de la fonction rénale</term><term>Thrombopénie (sang)</term><term>Thrombopénie (virologie)</term><term>Études rétrospectives</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Foie</term><term>Infections à coronavirus</term><term>Rein</term></keywords><keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Coronavirus Infections</term><term>Leukocytosis</term><term>Thrombocytopenia</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Kidney</term><term>Liver</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Foie</term><term>Rein</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Coronavirus Infections</term><term>Kidney</term><term>Liver</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Hyperleucocytose</term><term>Infections à coronavirus</term><term>Thrombopénie</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Hyperleucocytose</term><term>Thrombopénie</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Leukocytosis</term><term>Thrombocytopenia</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Female</term><term>Hospitalization</term><term>Humans</term><term>Kidney Function Tests</term><term>Leukocyte Count</term><term>Male</term><term>Middle East Respiratory Syndrome Coronavirus</term><term>Retrospective Studies</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Coronavirus du syndrome respiratoire du Moyen-Orient</term><term>Femelle</term><term>Hospitalisation</term><term>Humains</term><term>Mâle</term><term>Numération des leucocytes</term><term>Tests de la fonction rénale</term><term>Études rétrospectives</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">There are no longitudinal data on the changes in hematologic, hepatic, and renal function findings in patients with Middle East respiratory syndrome coronavirus (MERS-CoV) infection.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">28444873</PMID><DateCompleted><Year>2017</Year><Month>06</Month><Day>12</Day></DateCompleted><DateRevised><Year>2017</Year><Month>06</Month><Day>12</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1751-553X</ISSN><JournalIssue CitedMedium="Internet"><Volume>39</Volume><Issue>3</Issue><PubDate><Year>2017</Year><Month>Jun</Month></PubDate></JournalIssue><Title>International journal of laboratory hematology</Title><ISOAbbreviation>Int J Lab Hematol</ISOAbbreviation></Journal><ArticleTitle>Hematologic, hepatic, and renal function changes in hospitalized patients with Middle East respiratory syndrome coronavirus.</ArticleTitle><Pagination><MedlinePgn>272-278</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1111/ijlh.12620</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">There are no longitudinal data on the changes in hematologic, hepatic, and renal function findings in patients with Middle East respiratory syndrome coronavirus (MERS-CoV) infection.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">This is a retrospective cohort study of 16 MERS-CoV patients, to describe the hematological, hepatic, and renal findings of patients with MERS-CoV.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">During the 21 days of observation, there was no significant change in the hepatic panel or creatinine tests. There was a significant increase in the mean ± SD of the white blood cell count from 8.3 ± 4.6 to 14.53 ± 7 (P value = 0.001) and an increase in mean ± SD of the absolute neutrophil count from 6.33 ± 4.2 to 12 ± 5.5 (P value = 0.015). Leukocytosis was observed in 31% (5/16) of the patients on day 1 and in 80% (4/5) on day 21. Transient leukopenia developed in 6% (1/16) of the patients on day 1 and in 13% (1/8) on day 8. None of the patients had neutropenia. Lymphopenia was a prominent feature with a rate of 44% (7/16) of the patients on day 1 and 60% (3/5) on day 21. Lymphocytosis was not a feature of MERS-CoV infection. Thrombocytopenia developed in 31% (5/16) of the patients on day 1 and 40% (2/5) on day 21. Thrombocytosis was not a prominent feature and was observed in 6% (1/16) of the patients on day 1 and 17% (1/6) on day 9.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Patients with MERS-CoV infection showed variable hematologic parameters over time. Lymphocytosis and neutropenia were not features of MERS-CoV infection.</AbstractText><CopyrightInformation>© 2017 John Wiley & Sons Ltd.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Al-Tawfiq</LastName><ForeName>J A</ForeName><Initials>JA</Initials><AffiliationInfo><Affiliation>Internal Medicine, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Indiana University School of Medicine, Indianapolis, Indiana, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hinedi</LastName><ForeName>K</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Internal Medicine, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Abbasi</LastName><ForeName>S</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Internal Medicine, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Babiker</LastName><ForeName>M</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Internal Medicine, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sunji</LastName><ForeName>A</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Internal Medicine, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eltigani</LastName><ForeName>M</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Internal Medicine, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>04</Month><Day>26</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Int J Lab Hematol</MedlineTA><NlmUniqueID>101300213</NlmUniqueID><ISSNLinking>1751-5521</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="Y">blood</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006760" MajorTopicYN="N">Hospitalization</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007668" MajorTopicYN="N">Kidney</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007677" MajorTopicYN="N">Kidney Function Tests</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007958" MajorTopicYN="N">Leukocyte Count</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007964" MajorTopicYN="N">Leukocytosis</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008099" MajorTopicYN="N">Liver</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D065207" MajorTopicYN="Y">Middle East Respiratory Syndrome Coronavirus</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013921" MajorTopicYN="N">Thrombocytopenia</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Middle East respiratory syndrome</Keyword><Keyword MajorTopicYN="N">biochemical characteristics</Keyword><Keyword MajorTopicYN="N">hematologic changes</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year><Month>05</Month><Day>27</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2016</Year><Month>11</Month><Day>21</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>4</Month><Day>27</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>6</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>4</Month><Day>27</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28444873</ArticleId><ArticleId IdType="doi">10.1111/ijlh.12620</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Arabie saoudite</li></country></list><tree><country name="Arabie saoudite"><noRegion><name sortKey="Al Tawfiq, J A" sort="Al Tawfiq, J A" uniqKey="Al Tawfiq J" first="J A" last="Al-Tawfiq">J A Al-Tawfiq</name></noRegion><name sortKey="Abbasi, S" sort="Abbasi, S" uniqKey="Abbasi S" first="S" last="Abbasi">S. Abbasi</name><name sortKey="Babiker, M" sort="Babiker, M" uniqKey="Babiker M" first="M" last="Babiker">M. Babiker</name><name sortKey="Eltigani, M" sort="Eltigani, M" uniqKey="Eltigani M" first="M" last="Eltigani">M. Eltigani</name><name sortKey="Hinedi, K" sort="Hinedi, K" uniqKey="Hinedi K" first="K" last="Hinedi">K. Hinedi</name><name sortKey="Sunji, A" sort="Sunji, A" uniqKey="Sunji A" first="A" last="Sunji">A. Sunji</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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